Urolithin B

CAS No. 1139-83-9

Urolithin B( —— )

Catalog No. M22685 CAS No. 1139-83-9

Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK.?Urolithin B is also a regulator of skeletal muscle mass.Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 35 In Stock
25MG 63 In Stock
50MG 110 In Stock
100MG 177 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Urolithin B
  • Note
    Research use only, not for human use.
  • Brief Description
    Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK.?Urolithin B is also a regulator of skeletal muscle mass.Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects.
  • Description
    Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK.?Urolithin B is also a regulator of skeletal muscle mass.Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    NF-κB
  • Recptor
    NF-κB| JNK| ERK| Akt| AMPK| Human Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1139-83-9
  • Formula Weight
    212.2
  • Molecular Formula
    C13H8O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:249 mg/mL(1173.42 mM)
  • SMILES
    Oc1ccc2c(c1)oc(=O)c1ccccc21
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lee G, et al. Anti-inflammatory and antioxidant mechanisms of urolithin B in activated microglia. Phytomedicine. 2019 Mar 1;55:50-57.
molnova catalog
related products
  • Iguratimod

    A novel disease-modifying antirheumatic drug that inhibits NF-kappaB (NF-κB) p65 subunit (RelA) phosphorylation and nuclear translocation without affecting IKBα degradation.

  • AM-0561

    AM-0561 (AM0561) is a highly potent inhibitor of NF-κB inducing Kinase (NIK) with Ki of 0.3 nM.

  • Ethyl caffeate

    Ethyl caffeate is a potent chemopreventive compound against skin carcinogenesis caused by solar UV exposure.